studies are purely speculative and would under any circumstances be undertaken with the full knowledge and agreement of the Director of the Division of Biology and Medicine and his associates.” Hamilton's 1952 project proposal includes the following: human studies andastatine chelating studies (Scott and Hamilton, Jan. 1952) of the calcium complex of Versene and Fe~; studies in animals, with diagnostic use in people a list of Hamilton's projects for 1952 includes the following: tracer studies (radio-scandium,radio-thallium, radio-tungsten) chelating studies (Ca EDTA) oral ingestion of fission products and plutonium in the monkey effects of heavy nuclei on biological systems radiation chemistry astatine studies radioautographic studies inhalation of tagged silicon dioxide folder 23: a letter from Hamilton to Walter Claus, Director of Biology and Medicine, makesreference to the Sunshine Project. Hamiltonis referring to reprints on the use of radio-strontium in human beingsin the following: "Frankly, in looking over all these reprints including those of the University Press, there is not too much of value, inasmuch as these patients were not followed up in any great detail. However, I discussed the matter with Dr. Stone, explaining the need for obtaining this information and the available hospital records of these patients, the majority of which weretreated at the University of California Medical Center, and he assured me that you would get all possible information pertaining to the matter and in particular to changesin the blood picture, and forward them to me as soon as possible. He is aware of the significance of this "Sunshine Project” and I told him that he should be the only person in the San Francisco area that would be aware of the importance ofthis particular project even though several members of his organization have "Q” clearances. As soon as the data that he can obtain is forwarded to me I will see that your office gets as much detail as can be gleaned from the hospital records of these patients.” (Jan 28, 54) Anotherletter to Claus (Feb 3, 54) refers to the disaster at Chalk River, where several people inhaled or ingested Strontium 90; Hamilton suggested that a follow-up of these people and those in contact with the clean-up could be useful to the Sunshine Project. Strontium 90 becomes retained in the skeleton after a few weeks; but, hesaid, it has a 60 hour Yttrium 90 daughter. A letter from two days later to Stone from Charles Dunham, Chief of Medical Branch, Division of Biology and Medicine, asked for follow-up information on people given radiostrontium in 1942 to help set maximum permissible concentrations of a variety of radioisotopes in water supplies, This was also sent to Claus, Hamilton, and John Lawrence. From 1941-1944, 8 patients received strontium lactate; 5 received radioactive strontium 88; and 3 received non-radioactive strontium lactate. There are charts among the records with information on these people (names, dates, dosages, etc.) The principle investigator on this project appears to have been Low-Beer. Lawrence Berkeley Laboratory Archives and Records Office Human Radiation Experiments Search and Retrieval Project Anna Berge Research Notes Electronic Document Title: Bancroft/EOL April 4, 1994 10

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